Topics will include lead compound discovery strategies; high-throughput screening and ‘in silico’ screening; exploration of structure-activity relationships; drug targets and molecular mechanisms of drug action; strategies for drug optimization. [3 units]
Category Archives: Chemical Biology
Chem 4OB3: Polymers and Organic Materials
Fundamentals of polymer structure, and the structure-property relationships that enable polymer applications in a wide array of products. Both traditional and modern polymerization methods are covered, with an emphasis on methods enabling the formation of advanced polymer architectures. [3 units]
Chembio 4OA3: Natural Products
A description of basic building blocks and reaction mechanisms involved in the biosynthesis of naturally occurring compounds. [3 units]
Chembio 30A3: Organic Mechanistic Tools for Chemical Biology
Chemistry and biology of primary metabolism. Synthesis, biosynthesis and degradation of carbohydrates, nucleotides, and proteins are compared and contrasted by studying reaction mechanisms and catalysis. [3 units]
Chem 30A3: Organic Synthesis
A survey of contemporary organic synthesis, including functional group manipulations, use of protecting groups, and strategic carbon-carbon bond forming reactions. Applications involving multistep syntheses of complex organic molecules will be presented. [3 units]
Chembio 3P03: Biomolecular Interactions and Kinetics
Principles of macromolecule-macromolecule and small molecule-macromolecule interactions, including ligands and drugs. Techniques for characterizing and quantifying biomolecular interactions in vitro and in vivo. Emerging technologies such as biological therapeutics as applied to pharmaco-dynamics and -kinetics. [3 units]
Chem 2PC3: Mathematical Tools for Chemical Problems
An introduction to vector calculus, differential equations and linear algebra – including solving linear equations, eigenvalues and eigenvectors – motivated by problems of chemical equilibrium and kinetics. [3 units]
Chem 2P03: Applications of Physical Chemistry
Chemical thermodynamics and kinetics and their application to biological, chemical and environmental systems. [3 units]
Chem 2LA3: Chemistry Lab
< Back Make sure to read over the lab manuals before going into lab. Ask the TAs for help if you are confused!
Chem 2AA3: Quantitative Chemical Analysis
The art and science of performing quantitative analysis on samples based on classical volumetric techniques and modern instrumental methods including electrochemistry, optical spectroscopy, and chromatography. [3 units]
