Chemistry and Chemical Biology
Chem 1A03: Introductory Chemistry I
A discussion of chemical fundamentals, including bonding, structure, reactivity, and energetics, with emphasis on applications to health, energy, and the environment. Laboratories highlight hands-on experimental techniques; tutorials support the development of problem-solving skills. [3 units]
Chem 1AA3: Introductory Chemistry II
A discussion of organic chemistry, chemical kinetics, acid-base equilibrium, and the energetics of phase transformations, with emphasis on relevant experimental techniques and solving real problems ranging from drug discovery to environmental chemistry. [3 units]
Chem 2A03: Quantitative Chemical Analysis
The art and science of performing quantitative analysis on samples based on classical volumetric techniques and modern instrumental methods including electrochemistry, optical spectroscopy, and chromatography. [3 units]
Chem 2OA3 / 2OG3: Organic Chemistry I
An introduction to organic chemistry with emphasis on the reactions of functional groups and an introduction to spectroscopic techniques for structure determination. [3 units]
Chem 2OB3 / 2OD3: Organic Chemistry II
Nucleophilic substitutions at carbonyl centres, aromatic chemistry, carbohydrates, applications of spectroscopic techniques in organic chemistry. [3 units]
Chembio 2P03: Physical Chemistry Tools for Chemical Biology
Chemical thermodynamics and kinetics and their application to biological, chemical and environmental systems. [3 units]
Chem 3OA3: Organic Synthesis
A survey of contemporary organic synthesis, including functional group manipulations, use of protecting groups, and strategic carbon-carbon bond forming reactions. Applications involving multistep syntheses of complex organic molecules will be presented. [3 units]
Chembio 30A3: Organic Mechanistic Tools for Chemical Biology
Chemistry and biology of primary metabolism. Synthesis, biosynthesis and degradation of carbohydrates, nucleotides, and proteins are compared and contrasted by studying reaction mechanisms and catalysis. [3 units]
Chembio 3P03: Biomolecular Interactions and Kinetics
Principles of macromolecule-macromolecule and small molecule-macromolecule interactions, including ligands and drugs. Techniques for characterizing and quantifying biomolecular interactions in vitro and in vivo. Emerging technologies such as biological therapeutics as applied to pharmaco-dynamics and -kinetics. [3 units]
Chem 4OB3: Polymers and Organic Materials
Fundamentals of polymer structure, and the structure-property relationships that enable polymer applications in a wide array of products. Both traditional and modern polymerization methods are covered, with an emphasis on methods enabling the formation of advanced polymer architectures. [3 units]
Chembio 4OA3: Natural Products
A description of basic building blocks and reaction mechanisms involved in the biosynthesis of naturally occurring compounds. [3 units]
Chembio 4OB3: Medicinal Chemistry – Drug Design and Development
Topics will include lead compound discovery strategies; high-throughput screening and ‘in silico’ screening; exploration of structure-activity relationships; drug targets and molecular mechanisms of drug action; strategies for drug optimization. [3 units]
MSCAF 